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PPIB Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P23284 |
|---|---|
| Clone Names | 81028123 |
| Gene ID | 5479 |
|---|---|
| Other Names | Peptidyl-prolyl cis-trans isomerase B, PPIase B, CYP-S1, Cyclophilin B, Rotamase B, S-cyclophilin, SCYLP, PPIB, CYPB |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP6687b was selected from the C-term region of human PPIB. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | PPIB |
|---|---|
| Synonyms | CYPB |
| Function | PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. |
| Cellular Location | Virion. Note=(Microbial infection) |
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Provided below are standard protocols that you may find useful for product applications.
Background
PPIB is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression.
References
Fang,F., Am. J. Pathol. 174 (1), 297-308 (2009)Stumpf,T., J. Biol. Chem. 283 (26), 18086-18098 (2008)
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