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MAML3 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q96JK9 |
|---|---|
| Clone Names | 80821027 |
| Gene ID | 55534 |
|---|---|
| Other Names | Mastermind-like protein 3, Mam-3, MAML3 (HGNC:16272) |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP6719b was selected from the C-term region of human MAML3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | MAML3 (HGNC:16272) |
|---|---|
| Function | Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. |
| Cellular Location | Nucleus speckle. Note=Nuclear, in a punctate manner |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
MAML3 acts as a transcriptional coactivator for NOTCH proteins. The protein has been shown to amplify NOTCH-induced transcription of HES1.
References
Tonon,G., Nat. Genet. 33 (2), 208-213 (2003)Lin,S.E., J. Biol. Chem. 277 (52), 50612-50620 (2002)
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