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MAPE Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P78395
Clone Names 80821029
Peptide ID 80821029
Additional Information
Gene ID 23532
Other Names Melanoma antigen preferentially expressed in tumors, Opa-interacting protein 4, OIP-4, Preferentially expressed antigen of melanoma, PRAME, MAPE, OIP4
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6720b was selected from the C-term region of human MAPE. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms MAPE, OIP4
Function Functions as a transcriptional repressor, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, RARB and RARG. Prevents retinoic acid-induced cell proliferation arrest, differentiation and apoptosis.
Cellular Location Nucleus. Cell membrane
Tissue Location Expressed in testis. Detected in samples of kidney, brain and skin.
Research Areas
Citations (0)

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MAPE is an antigen that is predominantly expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. This expression pattern is similar to that of other CT antigens, such as MAGE, BAGE and GAGE. However, unlike these other CT antigens, its gene is also expressed in acute leukemias.


Rezvani,K., Blood 113 (10), 2245-2255 (2009)Qin,Y., Leuk. Res. 33 (3), 384-390 (2009)Neumann,E., Cancer Res. 58 (18), 4090-4095 (1998)

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$ 80.00
Cat# BP6720b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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