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F10 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P00742
Clone Names 80513118
Peptide ID 80513118
Additional Information
Gene ID 2159
Other Names Coagulation factor X, Stuart factor, Stuart-Prower factor, Factor X light chain, Factor X heavy chain, Activated factor Xa heavy chain, F10
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6728b was selected from the C-term region of human F10. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name F10
Function Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting.
Cellular Location Secreted.
Tissue Location Plasma; synthesized in the liver.
Research Areas
Citations (0)

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F10 is the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting.


Alba,R., Blood 114 (5), 965-971 (2009)Borensztajn,K., Thromb. Res. 124 (2), 219-225 (2009)Larson,P.J., Biochemistry 37 (14), 5029-5038 (1998)

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$ 80.00
Cat# BP6728b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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