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FKBP5 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q13451
Clone Names 80513141
Peptide ID 80513141
Additional Information
Gene ID 2289
Other Names Peptidyl-prolyl cis-trans isomerase FKBP5, PPIase FKBP5, 51 kDa FK506-binding protein, 51 kDa FKBP, FKBP-51, 54 kDa progesterone receptor-associated immunophilin, Androgen-regulated protein 6, FF1 antigen, FK506-binding protein 5, FKBP-5, FKBP54, p54, HSP90-binding immunophilin, Rotamase, FKBP5, AIG6, FKBP51
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6731a was selected from the N-term region of human FKBP5. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name FKBP5
Synonyms AIG6, FKBP51
Function Immunophilin protein with PPIase and co-chaperone activities. Component of unligated steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). Plays a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors maintaining the complex into the cytoplasm when unliganded.
Cellular Location Cytoplasm. Nucleus.
Tissue Location Widely expressed, enriched in testis compared to other tissues
Research Areas
Citations (0)

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The protein is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein.


Pei,H., Cancer Cell 16 (3), 259-266 (2009)Sarginson,J.E., Am. J. Med. Genet. B Neuropsychiatr. Genet. (2009)

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$ 80.00
Cat# BP6731a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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