|Other Names||Mitochondrial import receptor subunit TOM70, Mitochondrial precursor proteins import receptor, Translocase of outer membrane 70 kDa subunit, TOMM70A, KIAA0719, TOM70|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP6745b was selected from the C-term region of human TOMM70A. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Receptor that accelerates the import of all mitochondrial precursor proteins.|
|Cellular Location||Mitochondrion outer membrane; Single-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
The translocase of outer mitochondrial membrane (TOM) complex is a multisubunit complex involved in the recognition, unfolding, and translocation of preproteins into the mitochondria.
Blesa,J.R., Gene 427 (1-2), 58-64 (2008)Chou,C.H., Mol. Biol. Cell 17 (9), 3952-3963 (2006)Edmonson,A.M., Cell Commun. Adhes. 9 (1), 15-27 (2002)
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