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KYNU Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q16719
Clone Names 81202062
Peptide ID 81202062
Additional Information
Gene ID 8942
Other Names Kynureninase {ECO:0000255|HAMAP-Rule:MF_03017}, 3713 {ECO:0000255|HAMAP-Rule:MF_03017}, L-kynurenine hydrolase {ECO:0000255|HAMAP-Rule:MF_03017}, KYNU {ECO:0000255|HAMAP-Rule:MF_03017}
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6768b was selected from the C-term region of human KYNU. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name KYNU {ECO:0000255|HAMAP-Rule:MF_03017}
Function Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity.
Cellular Location Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03017, ECO:0000269|PubMed:8706755}
Tissue Location Expressed in all tissues tested (heart, brain placenta, lung, liver, skeletal muscle, kidney and pancreas) Highest levels found in placenta, liver and lung. Expressed in all brain regions.
Research Areas
Citations (0)

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KYNU is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. KYNU is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway.


Christensen,M.,, J. Inherit. Metab. Dis. 30 (2), 248-255 (2007)

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$ 80.00
Cat# BP6768b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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