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EDNRB Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P24530
Clone Names 80513110
Peptide ID 80513110
Additional Information
Gene ID 1910
Other Names Endothelin B receptor, ET-B, ET-BR, Endothelin receptor non-selective type, EDNRB, ETRB
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6789b was selected from the C-term region of human EDNRB. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms ETRB
Function Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Expressed in placental stem villi vessels, but not in cultured placental villi smooth muscle cells
Research Areas
Citations (0)

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EDNRB is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene.


MacClellan,L.R.,, Stroke 40 (10), E550-E557 (2009)

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$ 80.00
Cat# BP6789b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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