FKBP11 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9NYL4 |
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Clone Names | 80513128 |
Gene ID | 51303 |
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Other Names | Peptidyl-prolyl cis-trans isomerase FKBP11, PPIase FKBP11, 19 kDa FK506-binding protein, 19 kDa FKBP, FKBP-19, FK506-binding protein 11, FKBP-11, Rotamase, FKBP11, FKBP19 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP6790b was selected from the C-term region of human FKBP11. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | FKBP11 |
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Synonyms | FKBP19 |
Function | PPIases accelerate the folding of proteins during protein synthesis. |
Cellular Location | Membrane; Single-pass membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
Background
FKBP11 belongs to the FKBP family of peptidyl-prolyl cis/trans isomerases, which catalyze the folding of proline-containing polypeptides. The peptidyl-prolyl isomerase activity of FKBP proteins is inhibited by the immunosuppressant compounds FK506 and rapamycin.
References
Rulten,S.L., et.al., Mamm. Genome 17 (4), 322-331 (2006)
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