|Other Names||Peptidyl-prolyl cis-trans isomerase FKBP11, PPIase FKBP11, 19 kDa FK506-binding protein, 19 kDa FKBP, FKBP-19, FK506-binding protein 11, FKBP-11, Rotamase, FKBP11, FKBP19|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP6790b was selected from the C-term region of human FKBP11. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||PPIases accelerate the folding of proteins during protein synthesis.|
|Cellular Location||Membrane; Single-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
FKBP11 belongs to the FKBP family of peptidyl-prolyl cis/trans isomerases, which catalyze the folding of proline-containing polypeptides. The peptidyl-prolyl isomerase activity of FKBP proteins is inhibited by the immunosuppressant compounds FK506 and rapamycin.
Rulten,S.L., et.al., Mamm. Genome 17 (4), 322-331 (2006)
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