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Chromogranin-C Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P13521 |
|---|---|
| Clone Names | 80808079 |
| Gene ID | 7857 |
|---|---|
| Other Names | Secretogranin-2, Chromogranin-C, Secretogranin II, SgII, Secretoneurin, SN, SCG2, CHGC |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP6796c was selected from the Center region of human Chromogranin-C. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | SCG2 |
|---|---|
| Synonyms | CHGC |
| Function | Neuroendocrine protein of the granin family that regulates the biogenesis of secretory granules. |
| Cellular Location | Secreted. Note=Neuroendocrine and endocrine secretory granules |
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Provided below are standard protocols that you may find useful for product applications.
Background
Chromogranin-C is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce the active peptide secretoneurin, which exerts chemotaxic effects on specific cell types, and EM66, whose function is unknown.
References
Li,L., et.al., Cell Death Differ. 15 (5), 879-888 (2008)
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