|Other Names||Secretogranin-2, Chromogranin-C, Secretogranin II, SgII, Secretoneurin, SN, SCG2, CHGC|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP6796c was selected from the Center region of human Chromogranin-C. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Secretogranin-2 is a neuroendocrine secretory granule protein, which is the precursor for biologically active peptides.|
|Cellular Location||Secreted. Note=Neuroendocrine and endocrine secretory granules|
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Provided below are standard protocols that you may find useful for product applications.
Chromogranin-C is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce the active peptide secretoneurin, which exerts chemotaxic effects on specific cell types, and EM66, whose function is unknown.
Li,L., et.al., Cell Death Differ. 15 (5), 879-888 (2008)
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