FSHB Antibody (Center T70) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P01225 |
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Clone Names | 80808114 |
Gene ID | 2488 |
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Other Names | Follitropin subunit beta, Follicle-stimulating hormone beta subunit, FSH-B, FSH-beta, Follitropin beta chain, FSHB |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP6797c was selected from the Center region of human FSHB. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | FSHB |
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Function | Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways (PubMed:2494176, PubMed:24692546). Follitropin is involved in follicle development and spermatogenesis in reproductive organs (PubMed:407105, PubMed:8220432). |
Cellular Location | Secreted. Note=Efficient secretion requires dimerization with CGA |
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Provided below are standard protocols that you may find useful for product applications.
Background
FSHB stimulates development of follicle and spermatogenesis in the reproductive organs.
References
Grigorova,M., et.al., J. Clin. Endocrinol. Metab. (2009)
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