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AADAC Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P22760
Clone Names 80924021
Additional Information
Gene ID 13
Other Names Arylacetamide deacetylase, AADAC, DAC
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6805b was selected from the C-term region of human AADAC. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name AADAC
Synonyms DAC
Function Displays cellular triglyceride lipase activity in liver, increases the levels of intracellular fatty acids derived from the hydrolysis of newly formed triglyceride stores and plays a role in very low-density lipoprotein assembly. Displays serine esterase activity in liver. Deacetylates a variety of arylacetamide substrates, including xenobiotic compounds and procarcinogens, converting them to the primary arylamide compounds and increasing their toxicity.
Cellular Location Endoplasmic reticulum membrane; Single-pass type II membrane protein. Microsome membrane; Single-pass type II membrane protein
Tissue Location Detected in liver (at protein level). Mainly expressed in liver, small intestine, colon, adrenal gland and bladder
Research Areas
Citations (0)
citation

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Background

Arylacetamide deacetylation is an important enzyme activity in the metabolic activation of arylamine substrates to ultimate carcinogens.

References

Saito,S., et.al., J. Hum. Genet. 48 (5), 249-270 (2003)

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$ 277.78
Cat# BP6805b
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Availability: 2 weeks
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