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DNM2 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P50570
Clone Names 90121097
Peptide ID 90121097
Additional Information
Gene ID 1785
Other Names Dynamin-2, DNM2, DYN2
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6843a was selected from the N-term region of human DNM2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name DNM2
Synonyms DYN2
Function Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones (By similarity). Plays an important role in vesicular trafficking processes, in particular endocytosis. Involved in cytokinesis.
Cellular Location Cytoplasm. Cytoplasm, cytoskeleton. Cell junction {ECO:0000250|UniProtKB:P39052}. Membrane, clathrin-coated pit {ECO:0000250|UniProtKB:P39052}. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cell junction, synapse. Midbody. Note=Colocalizes with CTTN at the basis of filopodia in hippocampus neuron growth zones (By similarity) Microtubule-associated. Also found in the postsynaptic density of neuronal cells. {ECO:0000250|UniProtKB:P39052}
Tissue Location Ubiquitously expressed.
Research Areas
Citations (0)

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Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Four alternatively spliced transcripts encoding different proteins have been described.


Beausoleil,S.A.,, Proc. Natl. Acad. Sci. U.S.A. 101 (33), 12130-12135 (2004)

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$ 80.00
Cat# BP6843a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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