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HARP Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9NZC9
Clone Names 81201010
Peptide ID 81201010
Additional Information
Gene ID 50485
Other Names SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1, 364-, HepA-related protein, hHARP, Sucrose nonfermenting protein 2-like 1, SMARCAL1, HARP
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6864c was selected from the Center region of human HARP. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms HARP
Function ATP-dependent annealing helicase that binds selectively to fork DNA relative to ssDNA or dsDNA and catalyzes the rewinding of the stably unwound DNA. Rewinds single-stranded DNA bubbles that are stably bound by replication protein A (RPA). Acts throughout the genome to reanneal stably unwound DNA, performing the opposite reaction of many enzymes, such as helicases and polymerases, that unwind DNA. May play an important role in DNA damage response by acting at stalled replication forks.
Cellular Location Nucleus. Note=Recruited to damaged DNA regions
Tissue Location Ubiquitously expressed, with high levels in testis.
Research Areas
Citations (0)

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HARP is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. This protein shows sequence similarity to the E. coli RNA polymerase-binding protein HepA.


Aharinejad,S.,, Circulation 120 (11 SUPPL), S198-S205 (2009)

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$ 80.00
Cat# BP6864c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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