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RASIP1 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q5U651
Clone Names 80924166
Peptide ID 80924166
Additional Information
Gene ID 54922
Other Names Ras-interacting protein 1, Rain, RASIP1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6870c was selected from the Center region of human RASIP1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function Required for the proper formation of vascular structures that develop via both vasculogenesis and angiogenesis. Acts as a critical and vascular-specific regulator of GTPase signaling, cell architecture, and adhesion, which is essential for endothelial cell morphogenesis and blood vessel tubulogenesis. Regulates the activity of Rho GTPases in part by recruiting ARHGAP29 and suppressing RhoA signaling and dampening ROCK and MYH9 activities in endothelial cells (By similarity). May act as effector for Golgi-bound HRAS and other Ras-like proteins. May promote HRAS- mediated transformation. Negative regulator of amino acid starvation-induced autophagy.
Cellular Location Cytoplasm, perinuclear region. Golgi apparatus, Golgi stack. Note=Associated with perinuclear vesicles. Is recruited to Golgi stacks by activated HRAS
Tissue Location Highly expressed in heart. Detected at lower levels in placenta and pancreas.
Research Areas
Citations (0)

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RASIP1 may act as effector for Golgi-bound HRAS and other Ras-like proteins. May promote HRAS-mediated transformation.


Mitin,N.Y.,, J. Biol. Chem. 279 (21), 22353-22361 (2004)

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$ 80.00
Cat# BP6870c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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