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SOD3 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P08294
Clone Names 80924211
Peptide ID 80924211
Additional Information
Gene ID 6649
Other Names Extracellular superoxide dismutase [Cu-Zn], EC-SOD, SOD3
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6871a was selected from the N-term region of human SOD3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SOD3
Function Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen.
Cellular Location Secreted, extracellular space. Note=99% of EC-SOD is anchored to heparan sulfate proteoglycans in the tissue interstitium, and 1% is located in the vasculature in equilibrium between the plasma and the endothelium
Tissue Location Expressed in blood vessels, heart, lung, kidney and placenta. Major SOD isoenzyme in extracellular fluids such as plasma, lymph and synovial fluid
Research Areas
Citations (0)

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SOD3 is a member of the superoxide dismutase(SOD) protein family. SODs are antioxidant enzymes that catalyze the dismutation of two superoxide radicals into hydrogen peroxide and oxygen. This protein is thought to protect the brain, lungs, and other tissues from oxidative stress. The protein is secreted into the extracellular space and forms a glycosylated homotetramer that is anchored to the extracellular matrix (ECM) and cell surfaces through an interaction with heparan sulfate proteoglycan and collagen. A fraction of the protein is cleaved near the C-terminus before secretion to generate circulating tetramers that do not interact with the ECM.


Stern,L.F.,, Cytogenet. Genome Res. 101 (2), 178 (2003)

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$ 80.00
Cat# BP6871a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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