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PAX8 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q06710 |
|---|---|
| Clone Names | 81110008 |
| Gene ID | 7849 |
|---|---|
| Other Names | Paired box protein Pax-8, PAX8 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP6874c was selected from the Center region of human PAX8. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | PAX8 |
|---|---|
| Function | Transcription factor for the thyroid-specific expression of the genes exclusively expressed in the thyroid cell type, maintaining the functional differentiation of such cells. |
| Cellular Location | Nucleus. |
| Tissue Location | Expressed in the excretory system, thyroid gland and Wilms tumors |
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Provided below are standard protocols that you may find useful for product applications.
Background
PAX8 is a member of the paired box (PAX) family of transcription factors. Members of this family contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes.
References
Ramos,H.E., et.al., Thyroid 19 (1), 61-68 (2009)
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