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FMR1 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q06787
Clone Names 90121125
Peptide ID 90121125
Additional Information
Gene ID 2332
Other Names Fragile X mental retardation protein 1, FMRP, Protein FMR-1, FMR1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6879a was selected from the N-term region of human FMR1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name FMR1
Function Translation repressor. Component of the CYFIP1-EIF4E- FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates translation repression (By similarity). RNA- binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs. Associated with polysomes. May play a role in the transport of mRNA from the nucleus to the cytoplasm. Binds strongly to poly(G), binds moderately to poly(U) but shows very little binding to poly(A) or poly(C).
Cellular Location Cytoplasm. Nucleus, nucleolus.
Tissue Location Highest levels found in neurons, brain, testis, placenta and lymphocytes. Also expressed in epithelial tissues and at very low levels in glial cells
Research Areas
Citations (0)

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FMR1 binds RNA and is associated with polysomes. This protein may be involved in mRNA trafficking from the nucleus to the cytoplasm.


Yuhas,J.,, Genet Test Mol Biomarkers 13 (6), 855-859 (2009)

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$ 80.00
Cat# BP6879a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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