DLX2 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q07687 |
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Clone Names | 90415018 |
Gene ID | 1746 |
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Other Names | Homeobox protein DLX-2, DLX2 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP6884c was selected from the Center region of human DLX2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | DLX2 |
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Function | Acts as a transcriptional activator (By similarity). Activates transcription of CGA/alpha-GSU, via binding to the downstream activin regulatory element (DARE) in the gene promoter (By similarity). Plays a role in terminal differentiation of interneurons, such as amacrine and bipolar cells in the developing retina. Likely to play a regulatory role in the development of the ventral forebrain (By similarity). May play a role in craniofacial patterning and morphogenesis (By similarity). |
Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
DLX2 is likely to play a regulatory role in the development of the ventral forebrain. It may play a role in craniofacial patterning and morphogenesis. Subcellular location: Nucleus (Potential).
References
Yerges,L.M., et.al., J. Bone Miner. Res. (2009)
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