|Other Names||Guanine nucleotide-binding protein G(olf) subunit alpha, Adenylate cyclase-stimulating G alpha protein, olfactory type, GNAL|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP6893a was selected from the N-term region of human GNAL. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(olf) alpha mediates signal transduction within the olfactory neuroepithelium and the basal ganglia. May be involved in some aspect of visual transduction, and in mediating the effect of one or more hormones/neurotransmitters.|
|Tissue Location||Detected in olfactory neuroepithelium, brain, testis, and to a lower extent in retina, lung alveoli, spleen Trace amounts where seen in kidney, adrenal gland and liver. Found to be expressed in all the insulinomas examined|
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Provided below are standard protocols that you may find useful for product applications.
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(olf) alpha mediates signal transduction within the olfactory neuroepithelium and the basal ganglia. It may be involved in some aspect of visual transduction, and in mediating the effect of one or more hormones/neurotransmitters.
Laurin,N., et.al., J Psychiatr Res 42 (2), 117-124 (2008)
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