RAGE Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9UQ07 |
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Clone Names | 90415125 |
Gene ID | 5891 |
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Other Names | MAPK/MAK/MRK overlapping kinase, MOK protein kinase, Renal tumor antigen 1, RAGE-1, MOK, RAGE, RAGE1 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP6910c was selected from the Center region of human RAGE. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | MOK |
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Synonyms | RAGE, RAGE1 |
Function | Able to phosphorylate several exogenous substrates and to undergo autophosphorylation. Negatively regulates cilium length in a cAMP and mTORC1 signaling-dependent manner. |
Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:Q9WVS4}. Cell projection, cilium {ECO:0000250|UniProtKB:Q9WVS4}. Nucleus {ECO:0000250|UniProtKB:Q9WVS4} |
Tissue Location | Expressed in heart, brain, lung, kidney, and pancreas, and at very low levels in placenta, liver and skeletal muscle. Detected in retina |
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Provided below are standard protocols that you may find useful for product applications.
Background
RAGE is able to phosphorylate several exogenous substrates and to undergo autophosphorylation.
References
Peng,W.H., et.al., Arch. Med. Res. 40 (5), 393-398 (2009)
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