|Other Names||Interleukin-2, IL-2, T-cell growth factor, TCGF, Aldesleukin, IL2|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP6912c was selected from the Center region of human IL2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine- activated killer cells, natural killer cells, and glioma cells.|
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Provided below are standard protocols that you may find useful for product applications.
IL2 is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7(IL7).
Reyes-Gibby,C.C., et.al., Cancer Epidemiol. Biomarkers Prev. 18 (10), 2636-2642 (2009)
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