|Other Names||Tryptophan 5-hydroxylase 1, Tryptophan 5-monooxygenase 1, TPH1, TPH, TPRH, TRPH|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP6930a was selected from the N-term region of human TPH1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||TPH, TPRH, TRPH|
|Tissue Location||Isoform 2 seems to be less widely expressed than isoform 1|
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Provided below are standard protocols that you may find useful for product applications.
TPH1 is a member of the aromatic amino acid hydroxylase family. This protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter.
Johansson,T.A., et.al., BMC Cancer 9, 321 (2009)Kuhn,D.M., et.al., J. Neurochem. 68 (5), 2220-2223 (1997)
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