|Other Names||Tyrosine 3-monooxygenase, Tyrosine 3-hydroxylase, TH, TH, TYH|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP6945b was selected from the C-term region of human TH. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Plays an important role in the physiology of adrenergic neurons.|
|Tissue Location||Mainly expressed in the brain and adrenal glands|
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Provided below are standard protocols that you may find useful for product applications.
TH is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons.
Kuhn,D.M., et.al., J. Biol. Chem. 277 (16), 14336-14342 (2002)
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