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RAB6 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P20340 |
|---|---|
| Clone Names | 81110016 |
| Gene ID | 5870 |
|---|---|
| Other Names | Ras-related protein Rab-6A, Rab-6, RAB6A, RAB6 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP6956c was selected from the Center region of human RAB6. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | RAB6A |
|---|---|
| Synonyms | RAB6 |
| Function | Regulator of COPI-independent retrograde transport from the Golgi apparatus towards the endoplasmic reticulum (ER) (PubMed:25962623). Has a low GTPase activity (PubMed:25962623). Recruits VPS13B to the Golgi membrane (PubMed:25492866). Plays a role in neuron projection development (Probable). |
| Cellular Location | Golgi apparatus membrane; Lipid- anchor. Cytoplasmic vesicle, secretory vesicle, acrosome membrane {ECO:0000250|UniProtKB:P35279}; Peripheral membrane protein. Note=BICD2 facilitates its targeting to Golgi apparatus membrane. [Isoform 2]: Golgi apparatus membrane; Lipid-anchor |
| Tissue Location | Ubiquitous.. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
RAB6 is the regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER). It has a low GTPase activity.
References
Burguete,A.S., et.al., Cell 132 (2), 286-298 (2008)
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