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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   NOS3 Antibody (N-term) Blocking Peptide   

NOS3 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P29474
Clone Names 80325169
Peptide ID 80325169
Additional Information
Gene ID 4846
Other Names Nitric oxide synthase, endothelial, Constitutive NOS, cNOS, EC-NOS, Endothelial NOS, eNOS, NOS type III, NOSIII, NOS3
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6963a was selected from the N-term region of human NOS3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name NOS3
Function Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.
Cellular Location Cell membrane. Membrane, caveola. Cytoplasm, cytoskeleton. Golgi apparatus. Note=Specifically associates with actin cytoskeleton in the G2 phase of the cell cycle; which is favored by interaction with NOSIP and results in a reduced enzymatic activity
Tissue Location Platelets, placenta, liver and kidney.
Research Areas
Citations (0)

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Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases.


Rikova,K.,, Cell 131 (6), 1190-1203 (2007)

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$ 80.00
Cat# BP6963a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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