|Other Names||Protein bicaudal C homolog 1, Bic-C, BICC1|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP6966a was selected from the N-term region of human BICC1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Putative RNA-binding protein. Acts as a negative regulator of Wnt signaling. May be involved in regulating gene expression during embryonic development.|
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Provided below are standard protocols that you may find useful for product applications.
BICC1 is an RNA-binding protein that is active in regulating gene expression by modulating protein translation during embryonic development. Mouse studies identified the corresponding protein to be under strict control during cell differentiation and to be a maternally provided gene product.
Grupe,A., et.al., Am. J. Hum. Genet. 78 (1), 78-88 (2006)
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