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MSRB2 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9Y3D2
Clone Names 90504107
Additional Information
Gene ID 22921
Other Names Methionine-R-sulfoxide reductase B2, mitochondrial, MsrB2, 184-, MSRB2, CBS-1, MSRB
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6980c was selected from the Center region of human MSRB2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name MSRB2
Synonyms CBS-1, MSRB
Function Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue. Upon oxidative stress, may play a role in the preservation of mitochondrial integrity by decreasing the intracellular reactive oxygen species build-up through its scavenging role, hence contributing to cell survival and protein maintenance.
Cellular Location Mitochondrion.
Tissue Location Ubiquitous. Detected in retina, ocular ciliary body, skeletal muscle, heart, colon, bone marrow, cerebellum, small intestine, fetal brain, fetal liver, kidney, spinal cord, lung, placenta and prostate.
Research Areas
Citations (0)
citation

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Background

MSRB2 catalyzes the reduction of free and protein-bound methionine sulfoxide to methionine.

References

Cabreiro,F., et.al., J. Biol. Chem. 283 (24), 16673-16681 (2008)

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$ 277.78
Cat# BP6980c
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Availability: 2 weeks
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