|Other Names||Lymphocyte activation gene 3 protein, LAG-3, Protein FDC, CD223, LAG3, FDC|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP6987c was selected from the Center region of human LAG3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Involved in lymphocyte activation. Binds to HLA class-II antigens.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||On cell surface of activated NK and T- lymphocytes|
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Provided below are standard protocols that you may find useful for product applications.
Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains.
Smyth,D.J., et.al., BMC Med. Genet. 7, 20 (2006)
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