|Other Names||Serine/threonine-protein kinase RIO2, RIO kinase 2, RIOK2|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP7009b was selected from the C-term region of human RIOK2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
RIOK2 belongs to the protein kinase superfamily; RIO-type Ser/Thr kinase family. Serine/threonine protein kinases, such as RIOK2, phosphorylate the OH group of serine or threonine (which have similar sidechains). Activity of these protein kinases can be regulated by specific events (e.g. DNA damage), as well as numerous chemical signals, including cAMP/cGMP, Diacylglycerol, and Ca2+/calmodulin.
Ota, T., et al., Nat. Genet. 36(1):40-45 (2004).
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