|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP7011c was selected from the N-term region of human MSK2 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
MSK2 is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including CREB1 and c-fos. It has an essential role in the control of RELA transcriptional activity in response to TNF
Zhu, S., et al., Hum. Genet. 103(6):674-680 (1998).Pierrat, B., et al., J. Biol. Chem. 273(45):29661-29671 (1998).Deak, M., et al., EMBO J. 17(15):4426-4441 (1998).
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