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PXK Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q7Z7A4
Other Accession Q32NE9
Clone Names 50908205
Additional Information
Gene ID 54899
Other Names PX domain-containing protein kinase-like protein, Modulator of Na, K-ATPase, MONaKA, PXK (HGNC:23326)
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7017a was selected from the N-term region of human PXK. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PXK (HGNC:23326)
Function Binds to and modulates brain Na,K-ATPase subunits ATP1B1 and ATP1B3 and may thereby participate in the regulation of electrical excitability and synaptic transmission. May not display kinase activity.
Cellular Location Cytoplasm. Cell membrane; Peripheral membrane protein. Note=Also associates with the plasma membrane. Isoform 3 is present throughout the cell
Tissue Location Widely expressed in all tissues examined except in heart. Isoform 1 is expressed in high levels in the brain, skeletal muscle, spleen and testis. Isoform 7 expression has yet to be demonstrated.
Research Areas
Citations (0)
citation

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Background

PXK is widely expressed in all tissues examined except in heart. It binds to and modulates brain Na,K-ATPase subunits ATP1B1 and ATP1B3 and may thereby participate in the regulation of electrical excitability and synaptic transmission. However, the protein kinase domain is predicted to be catalytically inactive.

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$ 277.78
Cat# BP7017a
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