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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   PKC nu Antibody (C-term) Blocking Peptide   

PKC nu Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O94806
Clone Names 2041703
Peptide ID 2041703
Additional Information
Gene ID 23683
Other Names Serine/threonine-protein kinase D3, Protein kinase C nu type, Protein kinase EPK2, nPKC-nu, PRKD3, EPK2, PRKCN
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7025b was selected from the C-term region of human PKC nu . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PRKD3
Synonyms EPK2, PRKCN
Function Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress (By similarity).
Cellular Location Cytoplasm. Membrane. Note=Translocation to the cell membrane is required for kinase activation
Tissue Location Ubiquitous.
Research Areas
Citations (0)

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Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. PKC nu is one of the PKC family members. This kinase can be activated rapidly by the agonists of G protein-coupled receptors. It resides in both cytoplasm and nucleus, and its nuclear accumulation is found to be dramatically enhanced in response to its activation. This kinase can also be activated after B-cell antigen receptor (BCR) engagement, which requires intact phopholipase C gamma and the involvement of other PKC family members.


Yeaman, C., et al., Nat. Cell Biol. 6(2):106-112 (2004).Rey, O., et al., J. Biol. Chem. 278(26):23773-23785 (2003).Matthews, S.A., et al., J. Biol. Chem. 278(11):9086-9091 (2003).Bennasser, Y., et al., Virology 303(1):174-180 (2002).Bennasser, Y., et al., FASEB J. 16(6):546-554 (2002).

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$ 80.00
Cat# BP7025b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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