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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   Guanylate kinase (GUK1) Antibody (Center) Blocking peptide   

Guanylate kinase (GUK1) Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q16774
Clone Names 4011910
Peptide ID 4011910
Additional Information
Gene ID 2987
Other Names Guanylate kinase, GMP kinase, GUK1, GMK
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7070b was selected from the Center region of human GUK1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GUK1
Synonyms GMK
Function Essential for recycling GMP and indirectly, cGMP.
Research Areas
Citations (0)

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Guanylate kinase catalyzes the transfer of phosphate from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) or dGMP. This enzyme functions in the recovery of cGMP and is, therefore, thought to regulate the supply of guanine nucleotides to signal transduction pathways. The GUK2 and GUK3 isoforms are determined by separate loci. Brady et al. (1996) cloned human and mouse cDNAs of GUK1. They stated that the guanylate kinases are targets for cancer chemotherapy and are inhibited by the antitumor drug 6-thioguanine. They reported that the human gene codes for a protein of 197 amino acids with a mass of 21.7 kD. They found that the 1-kb message was ubiquitously expressed.


Brady, W. A., et al. J. Biol. Chem. 271: 16734-16740 (1996).

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$ 80.00
Cat# BP7070b
Availability: In Stock
Bulk Size
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