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NAGK Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9UJ70
Other Accession NP_060037
Clone Names 4012305
Peptide ID 4012305
Additional Information
Gene ID 55577
Other Names N-acetyl-D-glucosamine kinase, N-acetylglucosamine kinase, GlcNAc kinase, NAGK
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7080b was selected from the C-term region of human NAGK. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function Converts endogenous N-acetylglucosamine (GlcNAc), a major component of complex carbohydrates, from lysosomal degradation or nutritional sources into GlcNAc 6-phosphate. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway: although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded. Also has ManNAc kinase activity.
Tissue Location Ubiquitous..
Research Areas
Citations (0)

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N-acetylglucosamine kinase (NAGK) converts endogenous N-acetylglucosamine (GlcNAc), a major component of complex carbohydrates, from lysosomal degradation or nutritional sources into GlcNAc 6-phosphate. NAGK belongs to the group of N-acetylhexosamine kinases and is a prominent salvage enzyme of amino sugar metabolism in mammals. The predicted 344-amino acid NAGK protein contains the 5 sequence motifs necessary for the binding of ATP by sugar kinases. NAGK shares 91.6% amino acid similarity with mouse Nagk, for which enzyme activity is detectable in all mouse tissues examined, with highest enzymatic activity in testis. It is hypothesized that NAGK has a general role in the catabolic pathways of GlcNAc as well as of ManNAc.


Hinderlich, S., et al., Eur. J. Biochem. 267(11):3301-3308 (2000).Lowes, W., et al., Biochim. Biophys. Acta 1379(1):134-142 (1998).Weidanz, J.A., et al., Br. J. Haematol. 95(4):645-653 (1996).

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$ 80.00
Cat# BP7080b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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