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FASTK Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q14296
Clone Names 50908133
Peptide ID 50908133
Additional Information
Gene ID 10922
Other Names Fas-activated serine/threonine kinase, FAST kinase, FASTK
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7129a was selected from the Center region of human FASTK. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function Phosphorylates the splicing regulator TIA1, thereby promoting the inclusion of FAS exon 6, which leads to an mRNA encoding a pro-apoptotic form of the receptor.
Tissue Location Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas
Research Areas
Citations (0)

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FASTK is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis.


Li, W., et al., Mol. Cell. Biol. 24(24):10718-10732 (2004).Scherer, S.W., et al., Science 300(5620):767-772 (2003).Tian, Q., et al., J. Exp. Med. 182(3):865-874 (1995).Auffray, C., et al., C. R. Acad. Sci. III, Sci. Vie 318(2):263-272 (1995).

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$ 80.00
Cat# BP7129a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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Ordering Information

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