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PBK Antibody (C-term C300) Blocking PeptideSynthetic peptide
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| BP7164e | 0.1 mg 400 ul | In Stock | $ 45.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
PBK Antibody (C-term C300) Blocking Peptide - Product info | |
| Primary Accession | Q96KB5 |
| Clone Names | 6071560 |
| Calculated MW | 36085 Da |
PBK Antibody (C-term C300) Blocking Peptide - Additional info | |
| Gene ID 55872 | |
| Target/Specificity The synthetic peptide sequence used to generate the antibody AP7164e was selected from the C-term region of human PBK. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. | |
| Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. | |
| Precautions This product is for research use only. Not for use in diagnostic or therapeutic procedures. | |
PBK Antibody (C-term C300) Blocking Peptide - Protein Information | |
| Name PBK | |
| Synonyms TOPK | |
| Function Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin-induced DNA damage | |
| Tissue Location Expressed in the testis and placenta. In the testis, restrictedly expressed in outer cell layer of seminiferous tubules | |
PBK Antibody (C-term C300) Blocking Peptide - Related products
AP3577a: Phospho-PBK-pY74 Antibody
AP3633a: Phospho-PBK-pT9 Antibody
AP7164a: PBK Antibody (N-term)
AP7164b: PBK Antibody (C-term)
AP7164d: PBK Antibody (N-term N6)
AP7164e: PBK Antibody (C-term C300)
BP3577a: Phospho-PBK-pY74 Antibody Blocking Peptide
BP3633a: Phospho-PBK-pT9 Antibody Blocking Peptide
BP7164a: PBK Antibody (N-term) Blocking Peptide
BP7164b: PBK Antibody (C-term) Blocking Peptide
BP7164d: PBK Antibody (N-term N6) Blocking Peptide
BP7164e: PBK Antibody (C-term C300) Blocking Peptide
BP7164f: PBK Antibody (Y74) Blocking Peptide
AT3196a: PBK Antibody (monoclonal) (M06)
AT3197a: PBK Antibody (monoclonal) (M07)
AT3198a: PBK Antibody (monoclonal) (M11)
PBK Antibody (C-term C300) Blocking Peptide - Research Areas
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Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
PBK is a serine/threonine kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. This mitotic kinase may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis.
REFERENCES
Nandi, A., et al., Blood Cells Mol. Dis. 32(1):240-245 (2004).Simons-Evelyn, M., et al., Blood Cells Mol. Dis. 27(5):825-829 (2001).Zhao, S., et al., Int. J. Biochem. Cell Biol. 33(6):631-636 (2001).Abe, Y., et al., J. Biol. Chem. 275(28):21525-21531 (2000).Gaudet, S., et al., Proc. Natl. Acad. Sci. U.S.A. 97(10):5167-5172 (2000).
