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PGK2 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P07205
Clone Names 4012323
Peptide ID 4012323
Additional Information
Gene ID 5232
Other Names Phosphoglycerate kinase 2, Phosphoglycerate kinase, testis specific, PGK2, PGKB
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7170b was selected from the C-term region of human PGK2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PGK2
Synonyms PGKB
Function Essential for sperm motility and male fertility (PubMed:26677959). Not required for the completion of spermatogenesis (By similarity).
Cellular Location Cytoplasm.
Tissue Location Mainly found in round spermatids. Localized on the principle piece in the sperm (at protein level). Testis- specific. Expression significantly decreased in the testis of elderly men.
Research Areas
Citations (0)

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PGK2 is a form of phosphoglycerate kinase unique to spermatozoa. The autosomal PGK2 gene lacks introns and contains characteristics of a processed gene. The conservation of function in this processed PGK2 gene and its tissue-specific expression in spermatogenesis suggests that it exists as a compensatory response to the inactivation of the X-linked PGK1 gene in spermatogenic cells before meiosis.


Zhang, L.P., et al., Biol. Reprod. 60(6):1329-1337 (1999).McCarrey, J.R., et al., Dev. Genet. 19(4):321-332 (1996).Blanche, H., et al., Genomics 9(3):420-428 (1991).McCarrey, J.R., et al., Nature 326(6112):501-505 (1987).Michelson, A.M., et al., J. Biol. Chem. 260(11):6982-6992 (1985).

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$ 80.00
Cat# BP7170b
Availability: In Stock
Bulk Size
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