|Other Names||Phosphomevalonate kinase, PMKase, hPMK, PMVK, PMKI|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP7175a was selected from the C-term region of human PMVK. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Tissue Location||Heart, liver, skeletal muscle, kidney, and pancreas. Lower level in brain, placenta and lung|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
PMVK is a peroxisomal enzyme that catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate as the fifth reaction of the cholesterol biosynthetic pathway.
Hogenboom, S., et al., J. Lipid Res. 45(4):697-705 (2004).Strausberg RL, et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002).Olivier, L.M., et al., J. Lipid Res. 40(4):672-679 (1999).Chambliss, K.L., et al., J. Biol. Chem. 271(29):17330-17334 (1996).Krisans, S.K., et al., J. Biol. Chem. 269(19):14165-14169 (1994).
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.