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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   PRPS1/PRPS2/PRPS3 Antibody (C-term) Blocking peptide   

PRPS1/PRPS2/PRPS3 Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P60891
Other Accession Q5JV75
Clone Names 4012121
Peptide ID 4012121
Additional Information
Gene ID 5631
Other Names Ribose-phosphate pyrophosphokinase 1, PPRibP, Phosphoribosyl pyrophosphate synthase I, PRS-I, PRPS1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7178a was selected from the C-term region of human PRPS1/2/3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PRPS1
Function Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
Research Areas
Citations (0)

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Phosphoribosylpyrophosphate synthetase (PRPS) catalyzes the phosphoribosylation of ribose 5-phosphate to 5-phosphoribosyl-1-pyrophosphate, which is necessary for the de novo and salvage pathways of purine, pyrimidine, and pyridine biosynthesis. Defects in PRPS1 are the cause of PRPS-related gout, also known as gout due to PRPS1 superactivity. It is a familial disorder characterized by excessive purine production, gout and uric acid urolithiasis.


Ahmed, M., et al., J. Biol. Chem. 274(11):7482-7488 (1999).Ishijima, S., et al., Biochim. Biophys. Acta 1342(1):28-36 (1997).Becker, M.A., et al., J. Biol. Chem. 271(33):19894-19899 (1996).Roessler, B.J., et al., J. Biol. Chem. 268(35):26476-26481 (1993).Ishizuka, T., et al., Biochim. Biophys. Acta 1130(2):139-148 (1992).

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$ 80.00
Cat# BP7178a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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