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PHKG1 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q16816
Clone Names 3040906
Additional Information
Gene ID 5260
Other Names Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform, PHK-gamma-M, Phosphorylase kinase subunit gamma-1, Serine/threonine-protein kinase PHKG1, PHKG1, PHKG
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7232c was selected from the Center region of human PHKG1 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PHKG1
Synonyms PHKG
Function Catalytic subunit of the phosphorylase b kinase (PHK), which mediates the neural and hormonal regulation of glycogen breakdown (glycogenolysis) by phosphorylating and thereby activating glycogen phosphorylase. In vitro, phosphorylates PYGM, TNNI3, MAPT/TAU, GAP43 and NRGN/RC3 (By similarity).
Research Areas
Citations (0)
citation

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Background

This gene is a member of the Ser/Thr protein kinase family and encodes a protein with one protein kinase domain and two calmodulin-binding domains. This protein is the catalytic member of a 16 subunit protein kinase complex which contains equimolar ratios of 4 subunit types. The complex is a crucial glycogenolytic regulatory enzyme. This gene has two pseudogenes at chromosome 7q11.21 and one at chromosome 11p11.12.

References

Wehner, M., et al., Hum. Genet. 96(5):616-618 (1995).Jones, T.A., et al., Biochim. Biophys. Acta 1048(1):24-29 (1990).

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$ 277.78
Cat# BP7232c
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Availability: 2 weeks
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