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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   PHKG2 Antibody (N-term) Blocking Peptide   

PHKG2 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P15735
Clone Names 3040903
Peptide ID 3040903
Additional Information
Gene ID 5261
Other Names Phosphorylase b kinase gamma catalytic chain, liver/testis isoform, PHK-gamma-LT, PHK-gamma-T, PSK-C3, Phosphorylase kinase subunit gamma-2, PHKG2
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7233a was selected from the N-term region of human PHKG2 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PHKG2
Function Catalytic subunit of the phosphorylase b kinase (PHK), which mediates the neural and hormonal regulation of glycogen breakdown (glycogenolysis) by phosphorylating and thereby activating glycogen phosphorylase. May regulate glycogeneolysis in the testis. In vitro, phosphorylates PYGM (By similarity).
Research Areas
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Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.The calcium/calmodulin-dependent kinase (CAMK) group consists of 75 kinases regulated by Ca2+/CaM and close relative family (CAMK, CAMKL, DAPK, MAPKAPK).


Burwinkel, B., et al., Hum. Mol. Genet. 7(1):149-154 (1998).Maichele, A.J., et al., Nat. Genet. 14(3):337-340 (1996).Whitmore, S.A., et al., Genomics 20(2):169-175 (1994).Hanks, S.K., Mol. Endocrinol. 3(1):110-116 (1989).Hanks, S.K., Proc. Natl. Acad. Sci. U.S.A. 84(2):388-392 (1987).

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$ 80.00
Cat# BP7233a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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