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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   CDKL5 (STK9) Antibody (C-term) Blocking peptide   

CDKL5 (STK9) Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession O76039
Clone Names 3031901
Peptide ID 3031901
Additional Information
Gene ID 6792
Other Names Cyclin-dependent kinase-like 5, Serine/threonine-protein kinase 9, CDKL5, STK9
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7244b was selected from the C-term region of human STK9 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CDKL5
Synonyms STK9
Function Mediates phosphorylation of MECP2.
Cellular Location Nucleus.
Tissue Location Expressed in brain, lung, kidney, prostate, ovary, placenta, pancreas and testis
Research Areas
Citations (0)

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Defects in STK9, a dual-specificity serine/threonine kinase, are a cause of atypical Rett syndrome. Rett syndrome is an X-linked dominant disease. It is a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females. Patients appear to develop normally until 6 to 18 months of age, then gradually lose speech and purposeful hand movements and develop microcephaly, seizures, autism, ataxia, intermittent hyperventilation, and stereotypic hand movements. After initial regression, the condition stabilizes and patients usually survive into adulthood. Rett syndrome due to CDKL5-associated mutations is characterized by a severe early-onset phenotype and atypical features such as infantile spasms.


Kalscheuer, V.M., et al., Am. J. Hum. Genet. 72(6):1401-1411 (2003).Montini, E., et al., Genomics 51(3):427-433 (1998).

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$ 80.00
Cat# BP7244b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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