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NFE2L2-Y576 Antibody Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q16236
Other Accession NP_006155
Clone Names 80130110
Peptide ID 80130110
Additional Information
Gene ID 4780
Other Names Nuclear factor erythroid 2-related factor 2, NF-E2-related factor 2, NFE2-related factor 2, HEBP1, Nuclear factor, erythroid derived 2, like 2, NFE2L2, NRF2
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7275f was selected from the region of human NFE2L2-Y576 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name NFE2L2
Synonyms NRF2
Function Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.
Cellular Location Cytoplasm, cytosol. Nucleus. Note=Cytosolic under unstressed conditions, translocates into the nucleus upon induction by electrophilic agents
Tissue Location Widely expressed. Highest expression in adult muscle, kidney, lung, liver and in fetal muscle
Research Areas
Citations (0)

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NFE2 (MIM 601490), NFE2L1 (MIM 163260), and NFE2L2 comprise a family of human basic leucine zipper (bZIP) transcription factors. They share highly conserved regions that are distinct from other bZIP families, such as JUN (MIM 165160) and FOS (MIM 164810), although remaining regions have diverged considerably from each other (Chan et al., 1995).


Zhao,X., Stroke 38 (12), 3280-3286 (2007)Li,M.H., J. Biol. Chem. 282 (39), 28577-28586 (2007)

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$ 80.00
Cat# BP7275f
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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