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INS (Insulin) Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P01308
Clone Names 61228102
Additional Information
Gene ID 3630
Other Names Insulin, Insulin B chain, Insulin A chain, INS
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7277c was selected from the Center region of human INS. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name INS
Function Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
Cellular Location Secreted.
Research Areas
Citations (0)

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After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds. Binding of this mature form of insulin to the insulin receptor (INSR) stimulates glucose uptake.


Nordquist,L., Diabetes Metab. Res. Rev. 24 (2), 165-168 (2008)Nordquist,L., (er) Am. J. Physiol. Regul. Integr. Comp. Physiol. (2007) In pressNaya,T., Angiology 58 (6), 677-684 (2007)

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$ 80.00
Cat# BP7277c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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