|Other Names||Testis-specific serine kinase substrate, Testis-specific kinase substrate, STK22 substrate 1, TSKS, STK22S1, TSKS1|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP7280b was selected from the C-term region of human TSKS. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in testicular physiology, most probably in the process of spermatogenesis or spermatid development.|
|Cellular Location||Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Concentrates in spermatid centrioles during flagellogenesis|
|Tissue Location||Highly expressed in testis. Expressed at low levels in prostate, female breast, placenta, ovary and thymus|
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Provided below are standard protocols that you may find useful for product applications.
TSKS may play a role in testicular physiology, spermatogenesis or spermiogenesis. Expression of the encoded protein is highest in the testis and down-regulated in testicular cancer.
Hao,Z., Mol. Hum. Reprod. 10 (6), 433-444 (2004)Scorilas,A., Biochem. Biophys. Res. Commun. 285 (2), 400-408 (2001)
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