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NUDT6 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P53370 |
|---|---|
| Clone Names | 71211147 |
| Gene ID | 11162 |
|---|---|
| Other Names | Nucleoside diphosphate-linked moiety X motif 6, Nudix motif 6, 361-, Antisense basic fibroblast growth factor, Protein GFG, NUDT6, FGF2AS |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP7288b was selected from the C-term region of human NUDT6. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | NUDT6 |
|---|---|
| Synonyms | FGF2AS |
| Function | May contribute to the regulation of cell proliferation. |
| Cellular Location | Cytoplasm. Nucleus. Mitochondrion. Note=Subcellular location may vary between isoforms |
| Tissue Location | Detected in liver, kidney and esophagus (at protein level). Ubiquitous. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
FGF2 (MIM 134920) is a highly conserved, multifunctional heparin-binding growth factor involved in neuroectoderm development, angiogenesis, and wound healing. Elevated levels of FGF2 are associated with proliferation of smooth muscle in atherosclerosis and with proliferation of tumors. The FGF2 antisense gene, NUDT6, may regulate FGF2 expression.
References
Xiao,D.,Acta Biochim. Biophys. Sin. (Shanghai) 40 (4), 297-303 (2008)Zhang,S.C., J. Mol. Med. 85 (11), 1215-1228 (2007)Pezzatini,S., Bone 41 (4), 523-534 (2007)
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