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BTF3 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P20290
Clone Names 80102146
Peptide ID 80102146
Additional Information
Gene ID 689
Other Names Transcription factor BTF3, Nascent polypeptide-associated complex subunit beta, NAC-beta, RNA polymerase B transcription factor 3, BTF3, NACB
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7291b was selected from the C-term region of human BTF3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name BTF3
Synonyms NACB
Function When associated with NACA, prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. BTF3 is also a general transcription factor that can form a stable complex with RNA polymerase II. Required for the initiation of transcription.
Cellular Location Cytoplasm. Nucleus. Note=The heterodimer with NACA is cytoplasmic
Research Areas
Citations (0)

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Basic transcription factor 3 (BTF3)forms a stable complex with RNA polymerase IIB and is required for transcriptional initiation.


Green,C.D.,Mol. Cancer Res. 5 (11), 1191-1200 (2007)Kanno M., Gene 117:219-228(1992)Kusumawidjaja,G.,Cancer Biol. Ther. 6 (3), 367-376 (2007)

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$ 80.00
Cat# BP7291b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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