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Lefty (LEFTB) Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession O75610
Clone Names 71213135
Peptide ID 71213135
Additional Information
Gene ID 10637
Other Names Left-right determination factor 1, Left-right determination factor B, Protein lefty-1, Protein lefty-B, LEFTY1, LEFTB, LEFTYB
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7297b was selected from the C-term region of human LEFTB. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name LEFTY1
Synonyms LEFTB, LEFTYB
Function Required for left-right axis determination as a regulator of LEFTY2 and NODAL.
Cellular Location Secreted.
Research Areas
Citations (0)

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Background

LEFTB is a member of the TGF-beta family of proteins. A similar secreted protein in mouse plays a role in left-right asymmetry determination of organ systems during development. Alternative processing of this protein can yield three different products.

References

Kosaki K.,Am. J. Hum. Genet. 64:712-721(1999)Dvash,T.,Stem Cells 25 (2), 465-472 (2007)Besser,D.,J. Biol. Chem. 279 (43), 45076-45084 (2004)

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$ 80.00
Cat# BP7297b
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