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CA2 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P00918
Peptide ID 27935
Additional Information
Gene ID 760
Other Names Carbonic anhydrase 2, Carbonate dehydratase II, Carbonic anhydrase C, CAC, Carbonic anhydrase II, CA-II, CA2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CA2
Function Essential for bone resorption and osteoclast differentiation (By similarity). Reversible hydration of carbon dioxide. Can hydrate cyanamide to urea. Involved in the regulation of fluid secretion into the anterior chamber of the eye. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6.
Cellular Location Cytoplasm. Cell membrane. Note=Colocalized with SLC26A6 at the surface of the cell membrane in order to form a bicarbonate transport metabolon. Displaced from the cytosolic surface of the cell membrane by PKC in phorbol myristate acetate (PMA)-induced cells
Research Areas
Citations (0)

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CA2 is one of several (at least 7) isozymes of carbonic anhydrase. Carbonic anhydrase catalyzes reversible hydration of carbon dioxide. Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis.


Sultana, R., et al. Antioxid. Redox Signal. 12(3):327-336(2010)Fisher, S.Z., et al. Biochemistry 49(3):415-421(2010)Avvaru, B.S., et al. Biochemistry 49(2):249-251(2010)Maupin, C.M., et al. Biochemistry 48(33):7996-8005(2009)Avvaru, B.S., et al. Biochemistry 48(31):7365-7372(2009)

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$ 80.00
Cat# BP7307a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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